Melatonin ELISA 德國IBL現貨Enzyme immunoassay for the quantitative determination of melatonin in human serum and plasma.

Melatonin ELISA 德國IBL現貨The pineal gland (corpus pineale) has been called a neuroendocrine transducer because of its importantrole in photoperiodism. The major hormone of the pineal gland is N-acetyl-5-methoxy-tryptamine ormelatonin which is synthezised from the amino acid tryptophane. Melatonin has its highest levels in plasmaduring nighttime. Its characteristic nocturnal surge appears to encode temporal information such as length ofnight. Regulation of the melatonin secretion is under neural control. Sympathetic innervation seems to play amajor role via its release of noradrenaline. Altered patterns and/or levels of melatonin secretion have beenreported to coincide with sleep disorders, jet lag, depression, stress, schizophrenia, hypothalamicamenorrhea, pregnancy, anorexia nervosa, some forms of cancer, immunological disorders as well ascontrol of sexual maturation during puberty.Most of the circulating melatonin is metabolized in the liver to 6-hydroxymelatonin and subsequently to6-sulfatoxymelatonin which is excreted into the urine.The concentration of 6-hydroxymelatonin sulfate in urine correlates well with the total level of melatonin inthe blood during the collection period.